Nuclear calcium (Ca2+) is a major mediator of communication between synapses and nuclei and is critical for CREB-dependent gene expression. Mahoney, Ochoa Thomas and colleagues identify nuclear Ca2+ depletion as a pathomechanism connecting disease-associated forms of t...

We are looking to hire a postdoctoral fellow with expertise in transposon biology. The NIH-funded project focuses on the role of transposable elements in Alzheimer's disease, related tauopathies, and physiological brain aging. We work with Drosophila, iPSC-derived neur...

Dr. Frost is the recipient of the 2020 O'Donnell Award in Medicine from the Academy of Medicine, Engineering and Science of Texas based on her team's work on the effects of pathological forms of tau in the brain.

Elizabeth Ochoa Thomas, PhD candidate, and Marcus Phan, Frost lab summer student visiting from Howard University, represented UTHealthSA and the Frost lab at the 2019 Annual Biomedical Research Conference for Minority Students in Anaheim, CA. Elizabeth served on a pane...

New Frost lab postdoctoral fellow, Dr. Farzaneh Atrian, is now funded by an NIA-funded T32 Training Grant on the Biology of Aging. Dr. Atrian is investigating how brain aging affects the physical properties of neuronal nuclei. Well done, Farzaneh! And welcome to the fi...

Dr. Farzaneh Atrian Afyani has joined the Frost lab as a postdoctoral fellow. Dr. Atrian was recruited to the lab based on her previous studies in the laboratory of Dr. Sophie Lelievre, where she investigated the effects of tissue architecture on nuclear function.

Dr. Frost was awarded an RF1 (R01 equivalent) entitled "Investigating the role of transposable element dysregulation as a driver of neurotoxicity in tauopathy" from the National Institute on Aging and the National Institute on Neurological Disorders and Stroke. Click t...

Congratulations, Simon! We are proud of your continued leadership!

Congratulations to Simon Levy for receiving a travel award from the UTHSA Graduate School of Biological Sciences to attend the 2019 Neurodegenerative Disorders: New Insights and Therapeutic Opportunities Keystone Symposium in Keystone, CO.