PREPRINTS
1. Mozolewski P, Jeziorek M, Schuster CM, Bading H, Frost B, Dobrowolski R. (2021) The role of nuclear
Ca2+ in maintaining neuronal homeostasis and brain health. J Cell Sci. 134(8). PMCID: PMC8084578.
3. Ochoa Thomas E, Zuniga G, Sun W, Frost B (2020) Awakening the dark side: retrotransposon
activation in neurodegenerative disorders. Current Opinion in Neurobiology, 61:65-72. PMID: 32092528.
4. Cornelison G, Levy S, Jenson T, Frost B (2019) Tau-induced nuclear envelope invagination causes a toxic accumulation of mRNA in Drosophila. Aging Cell, 18(1):e12847. PMCID: PMC6351838.
5. Sun W, Samimi H, Gamez M, Zare H, Frost B (2018) Pathogenic tau-induced piRNA depletion
promotes neuronal death through transposable element dysregulation in neurodegenerative
tauopathies. Nature Neuroscience, 21(8):1038-1048. PMCID: PMC6095477.
6. Orr M, Sullivan C, Frost B (2017) A brief overview of tauopathy: Causes, consequences and
therapeutic strategies. Trends in Pharmacological Sciences, 38(7):637-648. PMCID: PMC5476494.
7. Sun W, Yan C, Frost B, Wang X, Hou C, Zeng M, Gao H, Kang Y, Liu J (2016) Pomegranate extract
decreases oxidative stress and alleviates mitochondrial impairment by activating AMPK-Nrf2 in
hypothalamic paraventricular nucleus of spontaneously hypertensive rats. Scientific Reports, 6:34246.
8. Frost B (2016) Alzheimer's disease: An acquired neurodegenerative laminopathy. Nucleus,
7(3):275-83. PMCID: PMC4991240.
9. Frost B, Bardai FH, Feany MB (2016) Lamin dysfunction mediates neurodegeneration in taupathies. Current Biology, 11;26(1):129-36. PMID: 26725200.
10. Frost B, Gotz J, Feany M (2015) Connecting the dots between tau dysfunction and
neurodegeneration. Trends in Cell Biology, 25(1):46-53. PMCID: PMC4275400.
11. Merlo P, Frost B, Peng S, Yang Y, Park P, Feany M (2014) p53 prevents neurodegeneration by
regulating synaptic genes. PNAS, 111(50):18055-60. PMCID: PMC4273405.
12. Frost B, Hemberg M, Lewis J, Feany M (2014) Tau promotes neurodegeneration through global
chromatin relaxation. Nature Neuroscience, 17(3):357-66. PMCID: PMC4012297.
13. Frost B, Diamond MI (2010) Prion-like mechanisms in neurodegenerative diseases. Nature Reviews
Neuroscience, 11(3)155-9. PMCID: PMC3648341.
14. Frost B, Diamond MI (2009) The expanding realm of prion phenomena in neurodegenerative
disease. Prion, 3(2)74-7. PMCID: PMC2712602.
15. Frost B, Jacks RL, Diamond MI (2009) Propagation of tau misfolding from the outside to the inside of
a cell. J Biol Chem., 284(19):12845-52. PMCID: PMC2676015.
16. Frost B, Ollesch J, Wille H, Diamond MI (2009) Conformational diversity of wild-type Tau fibrils
specified by templated conformation change. J Biol Chem., 284(6):3546-51. PMCID: PMC2635036.
SELECTED PUBLICATIONS
1. Ramirez P, Sun W, Zuniga G, Ochoa Thomas E, DeVos S, Hyman B, Chiu G, Roy ER, Orr M, Buggia-
Prevot V, Ray WJ, Frost B (2021) Pathogenic tau accelerates aging-associated activation of
transposable elements in the mouse central nervous system. bioRxiv,
https://www.biorxiv.org/content/10.1101/2021.02.25.432716v1.
2. Beckmann A, Ramirez P, Gamez M, Ray WJ, Frost B (2021) Pathogenic tau disrupts the cellular
program that maintains neuronal identity. bioRxiv,
https://www.biorxiv.org/content/10.1101/2021.03.05.434166v1.