NEWS

We are thrilled to introduce our newest team member, Melissa Soliz, who has joined us as a Research Associate in the Frost lab. Melissa brings a wealth of knowledge and expertise to our dynamic research environment. Melissa Soliz earned her Bachelor of Science degree in Biochemistry from the University of Texas at San Antonio, and her Master's degree in Immunology and Infection from the Graduate School of Biomedical Sciences at the UT Health Science Center in San Antonio. Mel

As we commemorate Dia de los Muertos, a day dedicated to honoring and remembering loved ones who have passed away, the Frost lab pays tribute to the brilliant scientists and dedicated doctors who have inspired us. We celebrate the lives and legacies of these remarkable individuals who have enriched our lives with their knowledge and dedication. As we honor their memory on Dia de los Muertos, we also celebrate the enduring impact of their work and strive to follow in their foo

The National Institute of General Medical Science blog "Biomedical Beat" showcases NIGMS-funded research and scientists, along with images and tools that help illustrate biomedical concepts and findings to the general public. Through the NIGMS, the NIH lays the foundation for advances in disease, diagnosis, treatment, and prevention. Abbey Bigler, a writer for the Biomedical Beat got a chance to catch up with Claira a few months ago to talk about her background, current event

August 15, 2023 In this review, I delve into mechanistic parallels between tauopathies, cancer, and development, and highlight the role of tau in cancer and in the developing brain. Based on these studies, I put forth a model by which pathogenic forms of tau disrupt the program that maintains terminal neuronal differentiation, driving cell cycle re-entry and consequent neuronal death. This framework presents tauopathies as conditions involving the profound toxic disruption of

We are proud to announce that Neuroscience PhD student Morgan Lambert was selected for support as a trainee on the UT Health San Antonio Neuroscience T32. This honor is a major stepping stone in the first stage of support from the NIH that can really jumpstart a scientific career.

Selective neuronal vulnerability to deficits in RNA processing Emerging evidence indicates that errors in RNA processing can causally drive neurodegeneration. Given that RNA produced from expressed genes of all cell types undergoes processing (splicing, polyadenylation, 5′ capping, etc.), the particular vulnerability of neurons to deficits in RNA processing calls for careful consideration. The activity-dependent transcriptome remodeling associated with synaptic plasticity in

Bess (and her father) helped MD/PhD student Zach Uttke and his girlfriend Melissa set up a hive!

Morgan Thomas absolutely rocked her qualifying exam! Comments from the committee included statements such as "this was one of the best QEs I've seen." Morgan is a T32-funded PhD student in the IBMS Neuroscience discipline. She is developing a split luciferase based reporter of polyglutamine aggregation in Drosophila and is studying the role of retrotransposons in microglial activation. Morgan also recently found out that she was accepted to the Summer Program in Neuroscience,

Zach Uttke is an MD/PhD student in our UT Health San Antonio MSTP program who joined the Frost lab for a summer prior to starting the program. We were particularly impressed by this poster award, as Zach has not even officially begun the PhD portion of his MD/PhD program! A quick intro to Zach's project: Throughout aging, decondensation of constitutive heterochromatin and consequent transcriptional de-repression occurs in species ranging from yeast to humans. A major function

We are pleased to announce that Morgan has accepted our offer to join the Frost lab for her PhD training! Morgan is in the Neuroscience Discipline of the Integrated BioMedical Sciences program at UT Health San Antonio. She earned her undergraduate degree in Biochemistry and Molecular biology with a minor in Neuroscience from the University of South Carolina. There she worked on detection of copper in the brain using carbon microfiber electrodes, and studied kynureninic acid i